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. 2014 Aug 13;8:82. doi: 10.3389/fnana.2014.00082

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Copyright © 2014 Radonjić, Ortega, Memi, Dionne, Jakovcevski and Zecevic.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sp8 in the human and mouse developing brain at mid-gestation. Expression of Sp8 mRNA (A) and protein (B) in the human fetal cortex. Immunohistochemistry in E12.5 mouse with anti-Sp8 antibody (C). (D) Representative immunolabeled Sp8⁺ cells in the human fetal cerebral cortex (15–20 gw). Sp8⁺ cells (green) co-labeled with (E) CalR (red) and (F) Gsx2 (red) in cortical plate and subplate. VZ, ventricular zone; iSVZ, inner subventricular zone; oSVZ, outer subventricular zone; IZ, intermediate zone; SP, subplate; CP, cortical plate; Cx, cortex; LV, lateral ventricle; CGE, caudal ganglionic eminence; MGE, medial ganglionic eminence. Scale bar, 50 μm.