Table 1.
PSMA in Vitro Inhibitory Activitiesa
compound | Ki (pM) |
---|---|
800CW-1 | 70 ± 5b |
800CW-2 | 40 ± 10b |
800CW-3 | 20 ± 5b |
800RS-1 | 100 ± 10cd |
800RS-2 | 200 ± 50b |
800RS-3 | 4 ± 0.5c |
ICG-1 | 700 ± 10cd |
ICG-2 | 400 ± 60cd |
ICG-3 | 200 ± 5cd |
Cy7-1 | 1 ± 0.5c |
Cy7-2 | 7 ± 0.4b |
Cy7-3 | 5 ± 0.2c |
Cy5.5-1 | 90 ± 40b |
Cy5.5-2 | 50 ± 20b |
Cy5.5-3 | 50 ± 2c |
Values are in Ki ± SEM.
n = 4.
n = 2.
Measured in DMSO; all others in water.