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Single-agent BCL-2 family inhibitor activity in AML cell lines. Seven AML-derived cells lines (TF-1, HEL, THP-1, U937, ML-2, HL-60 and MDS-L) are plotted for ABT-737, whereas 11 are plotted for ABT-199 activity (UKE-1, SET-2, M07e, TF-1, HEL, THP-1, ML-2, OCI-AML3, OCI-AML2, HL-60 and MDS-L). Six cell lines were tested with both compounds (TF-1, HEL, THP-1, ML-2, HL-60 and MDS-L).
