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. 2014 Feb 7;28(8):1636–1646. doi: 10.1038/leu.2014.19

Figure 1.

Figure 1

MGCD0103 decreases the levels of autophagy-related proteins in primary CLL cells. Immunoblotting analysis of protein extracts from PBMCs incubated in the absence or presence of MGCD0103 (0.5 or 3 μmol/l, as indicated) for 24 h. Autophagy-related proteins are indicated, as well as ACTB that was used as a loading control. (a) Shown are representative blots from the samples of 14 patients. The expression levels of SQSTM1 in MGCD0103-treated cells relative to the control and normalized to ACTB levels are indicated. (b, c) Shown are two representative blots from eight independent experiments.