Table 3.
Severity of acute and delayed nausea and vomiting
| Severitya | Mean±SD | P valueb (apripetant=no) |
P valueb (apripetant=yes) |
||
|---|---|---|---|---|---|
|
|
|||||
| Placebo group (n=46) |
Ginger 1.0 g group (n=43) |
Ginger 2.0 g group (n=40) |
|||
| Nausea | |||||
| Acute | |||||
| No apripetant | 2.8±1.3 (n=23) | 3.1±1.2 (n=21) | 3.0±1.1 (n=20) | 0.47 | 0.55 |
| Yes apripetant | 3.1±1.5 (n=8) | 2.8±1.1 (n=12) | 2.8±1.5 (n=10) | ||
| Delayed | |||||
| No apripetant | 3.0±1.3 (n=23) | 3.0±1.1 (n=25) | 3.2±1.1 (n=17) | 0.69 | 0.01 |
| Yes apripetant | 2.2±0.7 (n=9) | 2.9±1.3 (n=11) | 3.9±0.9 (n=9) | ||
| Vomiting | |||||
| Acute | |||||
| No apripetant | 3.6±1.4 (n=11) | 3.1±1.4 (n=14) | 2.9±0.9 (n=11) | 0.61 | 0.91 |
| Yes apripetant | 4.0±1.7 (n=3) | 3.4±0.6 (n=5) | 3.7±1.5 (n=6) | ||
| Delayed | |||||
| No apripetant | 4.0±1.3 (n=7) | 2.7±0.9 (n=12) | 3.7±1.0 (n=7) | 0.88 | 0.77 |
| Yes apripetant | 3.0±0.0 (n=1) | 3.0±1.4 (n=5) | 3.6±1.3 (n=5) | ||
a
Severity of nausea and vomiting graded on a six-point Likert scale graded as 1=very mild, 2=mild, 3=moderate, 4=severe, 5=very severe, and 6=intolerable
b
P values were calculated using Cochran Mantel–Haenszel tests stratified by apripetant (yes or no)