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Minimal criteria for mesenchymal stromal cell definition (International Society for Cellular Therapy)
| Adherence to plastic surfaces in standard culture conditions | ||
| Positive (> 95% +) | Negative (< 2% +) | |
| Immunophenotype | CD105 | CD45 |
| CD73 | CD34 | |
| CD90 | CD14 or CD11b | |
| CD79a or CD19 | ||
| HLA-DR | ||
| In vitro differentiation to osteoblasts, adipocytes and chondroblasts (demonstrated by appropriate staining of cell cultures) | ||
