Fig. 3.
Effects of PA on onset and duration of sleep in pentobarbital-treated mice. Mice were food deprived for 24 h prior to the experiment. Pentobarbital (40 mg/kg, i.p) was administered to mice following administration of muscimol or PA. The sleep latency (A) sleep time (B) were recorded. Each column represents the mean with S.E.M (n=10). The significance of the effects of the compounds was assessed using analysis of variance (ANOVA). Where there was significant variability, the individual values were compared using Dunnett’s- test. *p<0.05, **p<0.01, ***p<0.005, compared with that of control.