| 1. TBRI |
TGF-β receptor type I |
(30,31) |
| 2. TBRIITGF-β |
TGF-β receptor type II |
(31,32) |
| 3. cdh13herin |
Adhesion molecule, tumor suppressor |
(33,34) |
| 4. TTP (tristetrapolin) |
Loss of TTP stabilizes c-Myc mRNA |
(35) |
| 5. TGFBI (Betaig-h3) |
TGF-β induced gene |
(36-38) |
| 6. IGFBP3 |
IGF binding protein 3 |
(39,40) |
| 7. beta 4-integrin |
Promotes focal adhesion |
(34) |
| 8. MAL |
Promotes cell differentiation |
(41,42) |
| 9. SLIT2 |
Negative regulation of migration |
(36,41,43) |
| 10. Bcl2 |
Involved in apoptosis |
(40,41) |
| 11. Caspase 8 |
Pro-apoptotic gene |
(44) |
| 12. EPHA7 |
Tumor suppressor in prostate cancer |
(45-47) |
| 13. BTG3 |
Tumor suppressor |
(48,49) |
| 14. PTGS2 |
Pro-inflammatory enzyme |
(50-52) |
| 15. HIN1 (or SCGB3A1) |
Tumor suppressor |
(41,53) |
| 16. RASSF1A |
Tumor suppressor gene |
(54-56) |
| 17. CHD13 |
Adhesion molecule |
(41,57,58) |
| 18. p15, p16, p21, p27, p57 |
Cell cycle regulators |
(57,59-61) |
| 19. RASSF1A |
Pro-apoptotic, negative Ras effector |
(41,62) |
| 20. TWIST1 |
Suppressor of E-cadherin |
(41) |
| 21. FHIT |
Induces apoptosis though Bak |
(63,64) |
| 22. SOCS3 |
Negative regulator of cytokine |
(65,66) |
| 23. TIMP-2, TIMP-3 |
Inhibitors of metalloproteinase |
(67-69) |
| 24. PITX2 |
Activator of cyclin D2 |
(41,70-72) |
| 25. DcR1, DcR2 |
Fail to induced apoptosis through TRAIL |
(73,74) |
| 26. GLIPR1 (or RTVP-1) |
p53 target gene |
(75,76) |
| 27. MGMT |
DNA repair gene |
(77-81) |
| 28. DKK3 (SFRP1) |
Wnt antagonist |
(82,83) |
| 29. RUNX3 |
Tumor suppressor |
(84-86) |
| 30. CAV-1 |
Tumor suppressor |
(87,88) |
| 31. Clusterin |
Apoptotic protein |
(89-91) |
| 32. TFPI2 (PP5, MSPI) |
A potent inhibitor of matrix-metalloproteinases |
(92,93) |
| 33. SOX7 |
Suppressor of β-catenin |
(94,95) |
| 34. SLC5A8 |
Tumor suppressor |
(96,97) |
| 35. SLC18A2 (or VMAT2) |
Affects apoptosis and migration |
(98,99) |
| 36. LPL |
Tumor suppressor gene |
(100,101) |
| 37. HRK (or ATF-2) |
Proapoptosis |
(102,103) |
| 38. INHBB |
Inhibin betaB |
(104,105) |
| 39. ID4 |
Inhibitor of DNA binding |
(41,106-108) |
| 40. FYN |
Promotes proliferation and motility |
(109,110) |
| 41. HPP1 (TMEFF2) |
TGF-β signal pathway |
(73,84) |
| 42. RRAD |
Ras-related GTPases |
(111,112) |
| 43. DRM/Gremlin |
Down-regulated in Mos-transformed cells |
(73,84) |
