. Author manuscript; available in PMC: 2014 Aug 14.

Published in final edited form as: Eur J Phys Rehabil Med. 2013 Oct 30;49(6):877–892.

Table 1.

Studies and intervention Characeristics

	Groups	Program Type	Supervised session individual or group	Start of program	End of program	Session duration	Frequency	Intensity	Primasy measures	Secondary measures	Last follow-up

Evgeniadis et al. 2008	Intervention	Strengthening lower extremities	Home supervised	After discharge	8 weeks	Unknown	Unknown	Unknown	ILAS	AROM	14 weeks
	Control	No outpatiet therapy		Unknown	Unknown	Unknown	Unknown	Unknown	ILAS	AROM	14 weeks

Fung et al. 2012	Intervention	Strengthening exercise + 15 min of Wii-Fit game	Individual	Average 37 day after surgery	Average 54 days	60 minutes	Unknown	Exercised progressed	ROM; 2-minutes walk test; NPRS; LEFS; ABCS; LOR.		Unknown
Fung et al. 2012	Control	Strengthening exercise + 15 min additional lower leg strengthening	Individual	Average 46 day after surgery	Average 53 days	60 minutes	Unknown	Exercised progressed	ROM; 2-minutes walk test; NPRS; LEFS; ABCS; LOR.		Unknown

Harmer et al. 2009	Intervention	Water-basedtherapy	Individual	2 weeks postoperative	6 weeks	60 minutes	2/week	Exercised progressed	6MW	SCP; WOMAC; VAS pain; ROM	26 weeks
	Control	Land-based therapy	Individual	2 weeks postoperative	6 weeks	60 minutes	2/week	Exercised progressed	6MW	SCP; WOMAC; VAS pain; ROM	26 weeks

Johnson et al. 2010	Intervention	Strengthening exercises on whole body platform	Individual	One month	4 weeks	60 minutes	3/week	Exercised progressed	KISTR; CAR; TUG; VAS-pain; ROM		4 weeks
Johnson et al. 2010	Control	Strengthening exercises	Individual	One month	4 weeks	60 minutes	3/week	Exercised progressed	KISTR; CAR; TUG; VAS-pain; ROM		4 weeks

Kauppila et al. 2010	Intervention	Multidisciplinary rehabilitation	Group (n=?)	2/4 months postoperative	10 days	From 30 to 45 minutes	daily	Unknown	WOMAC	15MT; SCT; AROM; KISTR	12 months
	Control	Usual care	Unknown	Unknown	Unknown	Unknown	Unknown	Unknown	WOMAC	15MT; SCT; AROM; KISTR	12 months

Kramer et al. 2003	Intervention A	Clinic-based outpatient	Individual	Week 2 postoperative	Week 12 postoperative	1 hour	2/week	Exercised progressed	KSRS; WOMAC; MOSSF; 6MW; 30SST; AROM		12 months
Kramer et al. 2003	Intervention B	Home-based	Phone calls	Week 2 postoperative	Week 12 postoperative	Unknown	3/day	Unknown	KSRS; WOMAC; MOSSF; 6MW; 30SST; AROM		12 months

Levine et al. 2013	Intervention	NEMS + ROM exercise	Home-unsupervised	14 days preoperative	60 days postoperative	Unknown	Unknown	Unknown	KSRS; WOMAC; TUG		6 months
	Control	ROM + strengthening exercises	Clinic-based supervised	Unknown	Unknown	Unknown	Unknown	Unknown	KSRS; WOMAC; TUG		6 months

Liao et al. 2013	Intervention	Functional training + balance	Clinic-based supervised	Unknown	8 weeks	60 to 90 minutes	Unknown	Exercised progressed	FRT; SLST; 10MW; TUG; 30SCR; WOMAC		8 weeks
Liao et al. 2013	Control	Functional training	Clinic-based supervised	Unknown	8 weeks	60 minutes	Unknown	Exercised progressed	FRT; SLST; 10MW; TUG; 30SCR; WOMAC		8 weeks

Liebs et al. 2012	Intervention A	Satandard + aquatic therapy	Clinic-based supervised	6th postoperative day	up to 5 weeks	30 minutes	3/week	Unknown	WOMAC	SF-36; LKS	24 months
	Intervention B	Standard + aquatic therapy	Clinic-based supervised	14th postoperative day	up to 5 weeks	30 minutes	3/week	Unknown	WOMAC	SF-36; LKS	24 months

Madsen et al. 2013	Intervention	Strengthening andendurance exercises + educational sessions	Clinic-based group supervised (n=4 to 8)	4 to 8 weeks postoperative	6 weeks	Unknown	2/week	Exercised progressed	OKS; SF-36; EQ-5D	AROM; LEP; TT; 10MW; 30SCR; 5TSS; VAS-pain	6 months
Madsen et al. 2013	Control	Endurance, strengthening and fnctional exercises	Home-based	4 weeks postoperative	Unknown	Unknown	Unknown	Exercised progressed	OKS; SF-36; EQ-5D	AROM; LEP; TT; 10MW; 30SCR; 5TSS; VAS-pain	6 months

Mockford et al. 2008	Intervention	Standard therapy	Clinic-based supervised	Unknown	Unknown	Unknown	Unknown	Unknown	ROM; OKS; BPS; SF-12		12 months
	Control	No outpatiet therapy	Home-unsupervised	Unknown	Unknown	Unknown	Unknown	Unknown	ROM; OKS; BPS; SF-12		12 months

Moffet et al. 2004	Intervention	Intensive functional training	Clinic-based supervised	2 months potoperative	6 to 8 weeks	60 to 90 minutes	2/week	Exercised progressed	6MW	WOMAC; SF-36	12 months
Moffet et al. 2004	Control	Usual care	Unknown	Unknown	Unknown	Unknown	Unknown	Unknown	6MW	WOMAC; SF-36	12 months

Petterson et al. 2009	Intervention A	Progressive strengthening	Clinic-based supervised	3/4 weeks postoperative	6 weeks	Unknown	2or3/weeks	Exercised progressed	KISTR; CAR; TUG; SCT; 6MW	SF-36; KOS-ADL; AROM	12 months
	Control	Usual care	Unknown	Unknown	Unknown	Unknown	Unknown	Unknown	KISTR; CAR; TUG; SCT; 6MW	SF-36; KOS-ADL; AROM	12 months

Piva et al. 2010	Intervention	Functional training + balance	Clinic-based supervised	2/4 months postoperative	6 weeks	Unknown	2/week	Exercised progressed	WOMAC; LEFS	WS; SLTS; 5TSS	6 months^*
Piva et al. 2010	Control	Functional training	Clinic-based supervised	2/4 months postoperative	6 weeks	Unknown	2/week	Exercised progressed	WOMAC; LEFS	WS; SLTS; 5TSS	6 months^*

Rajan et al. 2004	Intervention	Outpatient therapy	Clinic-based supervised	Unknown	Unknown	Unknown	Unknown	Unknown	ROM		12 months
	Control	No outpatiet therapy	Unknown	Unknown	Unknown	Unknown	Unknown	Unknown	ROM		12 months

Russel et al. 2011	Intervention	Outpatient therapy	Home-remotely supervised	1 week postoperative	6 weeks	45 minutes	1/week	Unknown	WOMAC	PSFS; SQLU; TUG; VAS-pain	6 weeks
Russel et al. 2011	Control	Outpatient therapy	Clinic-based supervised	1 week postoperative	6 weeks	45 minutes	1/week	Unknown	WOMAC	PSFS; SQLU; TUG; VAS-pain	6 weeks

Tousignant et al. 2011	Intervention	Functional training	Home-remotely supervised	Unknown	8 weeks	60 minutes	2/week	Unknown	ROM; BBT; 30SCR	WOMAC; TUG; TinT; SMAF	4 months
	Control	Functional training	Home/Clinic supervised	Unknown	8 weeks	60 minutes	Unknown	Unknown	ROM; BBT; 30SCR	WOMAC; TUG; TinT; SMAF	4 months

Valtonen et al. 2010	Intervention	Outpatient aquatic therapy	Group-based supervised (n=4 to 5)	Average 10 months postoperative	12 weeks	60 minutes	2/week	Exercised progressed	WS; SCT; WOMAC; MP; MCSA		12 weeks^*
Valtonen et al. 2010	Control	No intervention	Unknown	Average 10 months postoperative	Unknown	Unknown	Unknown	Unknown	WS; SCT; WOMAC; MP; MCSA		12 weeks^*

Valtonen et al. 2011	Intervention	Outpatient aquatic therapy	Group-based supervised (n=4 to 5)	Average 10 months postoperative	12 weeks	60 minutes	2/week	Exercised progressed	WS; SCT; WOMAC; MP; MCSA		12 months^*
	Control	No intervention	Unknown	Average 10 months postoperative	Unknown	Unknown	Unknown	Unknown	WS; SCT; WOMAC; MP; MCSA		12 months^*

Time from randomization

Abbreviation: PCI, physiological cost index; HHS, Hospital of Special Surgery Scale; KRSR, Knee Society Rating Scale; AKS, American Knee Society clinical score; OKS, Oxford Knee Score; SF-36, short form 36; ILAS, Iowa lower extremity scale; AROM, active range of motion; ROM, range of motion; 2MW, two minute walk test; NPRS, numeric pain rating scale; LEFS, lower extremity functional scale; ABCS, activity specific balance confidence scale; LOR, length of outpatient physical therapy; 6MW, six-minutes walk test; SCP, stair climbing power; WOMAC, Western Ontario and McMaster Universities Arthritis Index; VAS, visual analog scale; 15D, Fifteen-dimensional quality of life, 15MT, Fifteen meters test; KISTR, Knee isometric strength; MOSSF, Medical outcome study short form; 30SST, thirty second stair test; FRT, functional reach test; SLST, single leg stance test; 10MW, Timed ten meters walk; 30SCR, Thirty second chair rise test; LKS, Lequense knee score; EQ-5D, Euro Qol-5Dimension; LEP, leg extensor power; TT, tandem test; 5TSS, Five time sit-to-stand; BPS, Bartlett patellar score; CAR, central activation ration; PSFS, patient specific functional scale; SQLU, Spitzer quality of life uniscale; GRS, global rating scale; SCT, stair climbing test; TUG, timed up-and-go test; BBT, berg balance test; TinT, Tinetti test; SMAF, Functional anatomy measurements system; MP, muscle power; MCSA, muscle cross sectional area.