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. 2014 Jul 15;2:23. doi: 10.1186/2051-1426-2-23

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Copyright © 2014 Dillon et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Cytokine production at different time points following helper peptide vaccination. Cytokine levels in 5-day supernatants are shown for 6 patients with proliferative responses to 6MHP vaccination whose PBMC were evaluated after stimulation with 6MHP. Th1 and Th2 cytokines are represented by stacked bars. The time in weeks after first vaccine is shown on the x-axis. The SIN was collected at day 22. The prior node for patient number 21 was collected prior to helper peptide vaccination and was analyzed with permission. It is included to illustrate the pre-vaccine cytokine milieu of the lymph nodes.