Figure 5.
Chromatin immunoprecipitation (ChIP) analysis of CXCL1 in skin tissue at day 1 after incision. Histone acetylation near the CXCL1 promoter in skin significantly increased at day 1 after incision in mice treated with morphine compared with mice treated with vehicle. Values are displayed as the mean ± SEM, n = 4, # p<0.05 vs. day 0 (before incision); ** p<0.01 vs. vehicle treated group. Veh=vehicle; Mor=morphine; INC= incision.