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. 2014 Aug 13;9(8):e104592. doi: 10.1371/journal.pone.0104592

Figure 7. PTER-ITC induces caspase-dependent apoptosis in breast cancer cells.

Figure 7

(A) Effects of 10 and 20 µM PTER-ITC on caspase-8, -9 and -3/7 activities in MCF-7 and MDA-MB-231 cells. Results are the mean ± SEM of three independent experiments. * indicates statistically significant difference relative to respective controls; p<0.05. (B) Effect of caspase inhibitors on PTER-ITC-induced apoptosis in MDA-MB-231 cells. Data shown as mean ± SEM of three independent experiments. * and # indicate statistically significant difference with respect to control and only PTER-ITC-treated cells, respectively; p<0.05.