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. 2014 Aug 13;9(8):e104555. doi: 10.1371/journal.pone.0104555

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© 2014 Mahony et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Each node is associated with a treatment tested in an RCT and each tie denotes a comparison between two treatments. The width of the ties among treatments denotes the number of times two treatments have been tested in RCTs. The network represents the connected component of the network depicted in Figure S1 in File S1 and it is comprised of 155 treatment comparisons. The most frequently tested comparison is between combination therapy and MP.