TABLE 3. Cross-Sectional and Longitudinal Studies: Pulmonary Function.

Study	N	Exposure	Scale		n	OR of AFL	Effect	Adjustments
Cross-sectional
Chan-Yeung et al5		Potroom		FEV1
	495	Yes	≥50% (H)	3,913
	713	Yes	<50% (M)	3,966
	302	No	Unexposed (U)	4,003			H−U: −90 mL; P = 0.029
Bakke et al4	658	Al-production	Ever vs never		39	1.5 (0.6–4.0)	—	—
Kongerud et al7	1760	Potroom	Duration of exposure, yr
		Yes	5–9 vs 0–4		NA	2.2 (1.4–3.5)
		Yes	≥10 vs 0–4		NA	2.6 (1.7–3.9)
Longitudinal						dFEV1
Chan-Yeung et al17		Potroom				mL/yr	Differences: mL/yr	Age, smoke, initial FEV1
	269	Yes	≥50% (H)	—	164	62,6	H−U: −0.93; P = −0.60
	171	Yes	<50% (M)	—	114	67.5	M−U: −1.24; P = −0.88
	380	No	Unexposed (U)	—	308	62.2
Søyseth et al18	630	Tot part	mg/m3		265		ΔFEV1: −11.9 mL/mg/m3; P = 0.004	Age, smoke, previous FEV1

AFL, airflow limitation; al-production, aluminum production or processing; dFEV₁, annual decline in FEV₁; FEV₁, forced expiratory volume in the first second of expiration; ΔFEV₁, mean difference of FEV₁ between two consecutive measurements; N, the total number of subjects in the cohort; n, the total number of subjects in the analyzes; NA, not applicable; OR, odds ratio; Tot part, Total particulates.