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. 2014 Jan 23;9(2):170–178. doi: 10.1097/JTO.0000000000000066

FIGURE 3.

FIGURE 3.

Expression of M3R in NSCLC is associated with airway obstruction and smoking. A, Differences in M3R expression in NSCLC tissues between patients with and without COPD. B, Inverse correlation between M3R expression and FEV1/FVC (r = 0.5057, p < 0.0001). C, Inverse correlation between M3R expression and %FEV1 (r = 0.7017, p < 0.0001). D, M3R expression levels in NSCLC patients with and without a smoking history. E, Correlation between M3R expression and smoking (pack-years) (r = 0.3169, p = 0.0014). M3R, muscarinic receptor 3; NSCLC, non–small-cell lung cancer; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; COPD, chronic obstructive pulmonary disease.