Table 2. Results of logistic regression analysis for Genotype and allele frequency of SNPs rs11720822 in PDIA5 and rs2754511 in BIRC6 in POAG, PCAG and PEXG patients and control individuals.
PDIA5 rs11720822 | POAG Est. | Z value | OR(95%CI) | P-value/pb | PACG Est. | Z value | OR(95%CI) | p-value/pb | PEXG Est. | Z value | OR(95%CI) | p-value/pb |
CC | 0.07 | 0.16 | 0.9 (0.37–2.26)a | 0.86/1.00b | 0.22 | −0.45 | 0.79 (0.29–2.13)a | 0.64/1.00b | 0.60 | 1.30 | 1.82(0.74–4.48)a | 0.18/1.00b |
CT | 17.90 | 0.02 | 5.95(0.00-Inf)a | 0.98/1.00b | 12.89 | 0.01 | 3.69 (0.00-Inf)a | 0.98/1.00b | 15.55 | 0.01 | 5.68(0.00-Inf)a | 0.98/1.00b |
TT | ||||||||||||
Allele Frequency | ||||||||||||
C | - | - | 0.74 (0.41–1.34)c | 0.28/1.00b | - | - | 1.00 (0.51–1.96)c | 0.99/1.00b | - | - | 1.15 (0.60–2.19)c | 0.66/1.00b |
T | - | - | - | - | - | - | ||||||
BIRC6 rs2754511 | ||||||||||||
AA | 0.39 | −2.53 | 0.67 (0.49–0.91)a | 0.01/0.06b | 0.05 | −0.28 | 0.94 (0.62–1.41)a | 0.77/1.00 | 0.35 | −1.87 | 0.70 (0.48–1.01)a 0.42 | 0.06/0.36b |
AT | 0.18 | 0.81 | 0.83 (0.52–1.30)a | 0.41/1.00b | 0.18 | 0.59 | 1.20 (0.65–2.22)a | 0.54/1.00b | 0.84 | 2.58 | (0.22–0.81)a | 0.009/0.05b |
TT | ||||||||||||
Allele Frequency | ||||||||||||
A | - | - | 0.85 (0.68–1.06)c | 0.15/0.90b | - | - | 0.95(0.72–1.26)c | 0.28/1.00b | - | - | 0.72 (0.55–0.94)c | 0.01/0.06b |
T | - | - | - | - | - | - |
Age and gender adjusted OR and (95%CI) from multivariate logistic regression analysis; pbBonferoni corrected p values; cOR and (95%CI) from univariate logistic regression analysis; Est., estimates