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. 2014 Aug 13;9(8):e104873. doi: 10.1371/journal.pone.0104873

Figure 3. C57BL/6 mice do not display clinical signs of pancreatitis following 75 days' treatment with liraglutide, exendin-4, or sitagliptin.

Figure 3

Reg3b immunoreactivity was assessed in pancreatic sections from mice treated with saline (Ai), liraglutide (B), exendin-4 (Aii, C) and sitagliptin (D), and normalised to Reg3b area observed in pancreata from saline treated mice, as described in ‘Materials and Methods’. Plasma amylase (E) and lipase (F) levels were measured after 75 days treatment with saline, liraglutide, exendin-4 or sitagliptin. ND, normal chow diet; HFD, high fat diet. p≤0.05, *; p≤0.01, **, n = 3–7 mice.