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. 2014 Aug 13;9(8):e104274. doi: 10.1371/journal.pone.0104274

Table 2. Comparison of MIPD Versus OPD (Pooled Analysis).

Outcome of interest Studies, n Patients, n OR/MD 95% CI P value Heterogeneity Test
P value I2
Intraoperative outcomes
Operative time,min 11 869 105 (49.73, 160.26) <0.001 <0.001 93%
Estimated blood loss, mL 10 746 −361.93 (−519.22 −204.63) <0.001 <0.001 94%
Postoperative outcomes
Morbidity, (%) 9 762 0.73 (0.53, 1.00) 0.05 0.35 10%
Wound infection, n 6 584 0.41 (0.22, 0.78) 0.007 0.86 0%
Overall pancreatic fistula, n 10 802 0.96 (0.65, 1.44) 0.86 0.88 0%
 Grade A 5 486 0.88 (0.47, 1.66) 0.7 0.86 0%
 Grade B 6 548 1.01 (0.46, 2.20) 0.98 0.89 0%
 Grade C 6 525 0.83 (0.37, 1.85) 0.64 0.87 0%
Overall delayed gastric emptying, n 11 869 0.99 (0.62, 1.56) 0.96 0.76 0%
 Grade A 3 386 0.82 (0.31, 2.19) 0.69 0.49 0%
 Grade B 4 446 0.77 (0.29, 2.02) 0.59 0.93 0%
 Grade C 3 365 1.23 (0.41, 3.71) 0.71 0.8 0%
Reoperation, n 8 721 0.63 (0.34, 1.19) 0.16 0.73 0%
Mortality, (%) 7 582 0.82 (0.37, 1.85) 0.64 0.93 0%
Length of stay, d 10 818 −2.64 (−4.23, −1.05) 0.001 <0.001 78%
Oncologic outcomes
Retrieved lymph nodes, n 7 612 1.15 (−2.02, 4.32) 0.48 <0.001 83%
Positive surgical margins,n 7 451 0.57 (0.31, 1.04) 0.07 0.12 40%