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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: J Allergy Clin Immunol. 2014 May 3;133(6):1667–1675. doi: 10.1016/j.jaci.2014.03.025

FIG 1.

FIG 1

DOCK8 immunodeficient patients having T cell reversions. A, Immunoblotting for DOCK8 or β-actin proteins in primary T cells, B cells, or monocytes. NC, normal healthy control. Patient 20 has a homozygous large deletion. Patients 12 and 10 have somatic repair. B, Representative flow cytometry histograms showing intracellular DOCK8 expression in gated subsets from a normal healthy control (black), DOCK8 heterozygous carrier (grey), Patient 19 with a large homozygous deletion (red), or isotype control staining (blue). C, Histograms are from Patient 12 who has somatic repair.