Table 1. Proteins predicted to interact with two or more binding partners of CACN-1.
| C. elegans Sequence ID | Locus | H. sapiens Gene | BLAST | Similarity (Identity)a | Functional Class | Description |
|---|---|---|---|---|---|---|
| C05D11.4 | let-756 | FGF20 | 6.9E-24 | 63% (42%) | Signaling | FGF-like ligand |
| C32F10.2 | lin-35 | RBL2 | 2.4E-45 | 42% (25%) | Signaling | Retinoblastoma protein homolog |
| F02A9.6 | glp-1 | NOTCH1 | 1.1E-88 | 39% (26%) | Signaling | Notch receptor |
| K06A5.7 | cdc-25.1 | CDC25.A | 2.0E-24 | 57% (36%) | Cell cycle | CDC25 phosphatase homolog |
| T07F8.3 | gld-3 | BICC1 | 9.0E-06 | 44% (20%) | Nucleic Acid binding | KH domain RNA-binding protein |
| Y55D5A.5 | daf-2 | INSR | 2.7E-143 | 54% (37%) | Signaling | Insulin/IGF receptor homolog |
Data derived from Wormbase WS241. FGF, fibroblast growth factor; IGF, insulin-like growth factor.
a
Within homologous region.