Table 2.
Lists of differentially regulated genes modified for each cell line as retrieved by IPA network analysis
| Genes | Fold |
|---|---|
|
OVCAR3 |
|
|
Adhesion, invasion and migration |
|
| TWIST |
2.85 |
| ZEB |
2 |
| CDH1 |
2.8 |
| Hyaluronan Synthase 3 |
-2.7 |
| FN1 |
-5.67 |
|
Proliferation |
|
| CEBPB |
5.3 |
| CCND2 |
5.4 |
| CDKN1C |
4.2 |
| BCL6 |
5.5 |
| RASGRP1 |
2.17 |
| CCNE2 |
-3.9 |
| GMNN |
-2 |
| SKP2 |
-2.2 |
| SPARC |
-3.8 |
|
Chemoresistance |
|
| GADD45A |
8.7 |
| DDIT3 |
9.7 |
| NR3C1 |
3 |
| ATF2 |
2.65 |
| RASGRP1 |
2.1 |
|
SKOV3 |
|
|
Adhesion, invasion and migration |
|
| CXCR4 |
2.9 |
| FN1 |
2 |
| MMP3 |
5.8 |
| Serpine1 |
3.2 |
| PAPP-A |
7.2 |
| SPARC |
4.6 |
| CDH1 |
-4.4 |
| CD24 |
-2.1 |
| VAV3 |
-2.9 |
|
Proliferation |
|
| INHBA |
3.5 |
| FN1 |
2 |
| IGFBP5 |
4.3 |
| SPARC |
4.6 |
| COL1A1 |
9.8 |
|
Chemoresistance |
|
| SPARC |
6.4 |
| PDGFRA |
4.5 |
| S1PR3 |
2.8 |
| KITLG |
2.2 |
| IGFBP5 |
4.4 |
| SCD |
-4.2 |
| FASN |
-2 |
| DDIT4 | -2.5 |