Table 2.

Stroke patients: correlations between biochemical markers, stroke severity, volume of infarct and stroke outcome

Values of spearman rho correlations:		IL-6		TNF-α		Glutamate
		IL-6	IL-6	TNF-α	TNF-α	Glu	Glu
		<12 h	72 h	<12 h	72 h	<12 h	72 h
Clinical severity (APACHE II)	All patients	0.261	0.326**	0,130	0,155	−0.076	−0.029
		−0.061	0.484**	−0,085	0,068	0.421*	−0.193
	Large infarcts	0.630***	0.433	0.244	0.347	−0.052	0.149
		−0.369	0.197	−0,821	−0,462	−0.350	−0.727**
	Medium infarcts	−0.066	0.241	0.190	0.044	−0.042	−0.007
		0.261	0.759**	-	0.400	0.374	0.410
Stroke severity (NIHSS)	All patients	0.068	0.497***	0.312	0.247	0.193	0.261*
		-	-	−0.488	−0.488	-	-
	Large infarcts	0.247	0.020	0.388	0.433	0.165	−0.013
		-	-	−0.866	−0.866	-	-
	Medium infarcts	−0.223	0.505***	−0.023	−0.108	0.217	0.371**
		-	-	−0.866	−0.866	-	-
Volume of infarct§	All patients	0.207	0.290**	0.476**	0.275	0.120	0.151
	Large infarcts	0.398	0.299	0.592*	0364	0.325	0.324
	Medium infarcts	0.069	−0.113	0.097	0.178	0.001	0.001
Clinical outcome: 3-months mRS	All patients	0.230	0.444***	0.352*	0.150	0.101	0.006
		-	-	0.546	−0.095	-	-
	Large infarcts	0.453*	0.455	0.370	0.283	0.235	0.295
		-	-	0.105	0.316	-	-
	Medium infarcts	0.042	0.273	0.338	0.120	−0.023	−0.080
		-	-	0.316	−0.738	-	-
Clinical outcome: 3-months Barthel index	All patients	−0.121	−0.245	−0.152	−0.109	−0.164	−0.017
		−0.492*	−0.303	−0.536	−0.009	0.092	0.433*
	Large infarcts	−0.366	−0.366	0.119	−0.444	−0.268	0.000
		−0.449	−0.338	−0.200	−0.300	−0.570	0.591*
	Medium infarcts	−0.053	−0.078	−0.262	0.168	−0.042	0.006
		−0.702*	0.025	−0.316	0.738	0.368	−0.495

The numbers in the upper line of each row correspond to stroke patients and the line below to controls.

*P < 0.1; **P < 0.05; ***P < 0.01. Results with P < 0.1 are in bold

^§Only stroke patients

APACHE II, Acute Physiology and Chronic Health Evaluation II scale; NIHSS, National Institutes of Health Stroke Scale.