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Systemic treatment recommendations according to subtypes [2]
| Subtype | Type of therapy |
|---|---|
| Luminal A like | endocrine therapy is the most critical intervention and is often used alone |
| Luminal B like (HER2 negative) | endocrine therapy for all patients, cytotoxic therapy for most |
| Luminal B like (HER2 positive) | cytotoxics + anti-HER2 + endocrine therapy |
| HER2 positive (non-luminal) | cytotoxics + anti-HER2 |
| Triple-negative | cytotoxics |
