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Parameter estimates and their bootstrap CIs from the pharmacokinetic model
| Parameter | Estimate (95% CI) | Literaturea |
|---|---|---|
| V1, l | 15.2 (11.2–21.5) | 10.3 |
| V2, l | 51.8 (26.8–99.5) | 35.7 |
| V3, l | 1070 (826–1990) | 772 |
| CL1, l/h | 55.9 (35.2–65.5) | 72.9 |
| CL2, l/h | 26.9 (17.5–42.0) | 30.2 |
| CL3, l/h | 73.8 (58.8–103) | 61.5 |
Values taken from [25]. V = Volume, CL = clearance.
