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Baicalein enhanced glucose-stimulated insulin secretion from β-cells and human pancreatic islets. INS382/13 cells (a) or islets (b) were incubated in KRB buffer with various concentrations of baicalein (B) in the presence of 3 mM or 20 mM glucose at 37°C for 30 min. Insulin secreted into supernatants was measured by ELISA. Data are expressed as means ± SEM from 6 experiments for INS382/13 cells and 3 experiments for human isles in duplicate each. *P < 0.05 versus control.
