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. 2013 Dec 4;35(31):2115–2122. doi: 10.1093/eurheartj/eht481

Table 4.

Change in the area under the curve for probable myocardial infarction, death and the composite of myocardial infarction or death with addition of (A) CXCL12 dataa and (B) estimated glomerular filtration rate data

(A) Add CXCL12 to model
ROC AUC in Model 2 ROC AUC in Model 2 + eGFR
Without CXCL12 With CXCL12 P-value Without CXCL12 With CXCL12 P-value
Probable MI 0.664 0.685 0.003 0.690 0.698 0.023
Death 0.674 0.695 <0.001 0.723 0.727 0.049
MI or death 0.660 0.680 <0.001 0.703 0.707 0.057
(B) Add eGFR to model
ROC AUC in Model 2 ROC AUC in Model 2 + CXCL12
Without eGFR With eGFR P-value Without eGFR With eGFR P-value
Probable MI 0.664 0.690 0.002 0.685 0.698 0.017
Death 0.674 0.723 <0.001 0.695 0.727 <0.001
MI or death 0.660 0.703 <0.001 0.680 0.707 <0.001

aStandardized plasma CXCL12 values.

Model 2: CXCL12 + demographic factors + traditional risk factors (diabetes, hypertension, hypercholesterolaemia, tobacco use, body mass index).