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. 2014 Jun 26;137(9):2444–2455. doi: 10.1093/brain/awu174

Figure 5.

Figure 5

Summary of interactions among (CAG)n-containing genes in the EUROSCA cohort. For the SCA type, the black labels indicate the gene, the blue label, the age at onset of individuals with an expansion of the gene. Black arrows are for marginal effect whether green arrows are for effect in interaction with the major gene. Nb > 12: = alleles with more than 12 repeats; Interm = intermediate allele; + = positive effect; – = negative effect; Shorter = shorter allele; Longer = longer allele; Longer > 25 = longer allele with >25 repeats; Difference = difference between the longer and the shorter allele.