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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Cell Signal. 2013 Aug 24;25(12):2518–2529. doi: 10.1016/j.cellsig.2013.08.004

Fig. 1.

Fig. 1

Prediction of JNK target phosphoacceptor sites close to a JNK-docking site.

A) Linear representation of known JNK targets ATF2, JUNB, and JUN with all potential ST/TPphosphosites shown. Those sites predicted by our PWM method to be likely JNK targets arelabeled as ‘JNK’. Literature-validated phosphosites are indicated with yellow crosses. The D-finder-predicted D-site is shown as a purple rectangle; the 100 amino acid window to either sideof the D-site is indicated by a thickened gray line. B) Linear representation of full-lengthSMTNL2 protein and all potential ST/TP phosphosites. Labeling as above. Phosphositesidentified in the mass spectrometry/mutagenesis experiments described further below areindicated with yellow crosses