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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Cell Signal. 2013 Aug 24;25(12):2518–2529. doi: 10.1016/j.cellsig.2013.08.004

Fig. 2.

Fig. 2

SMTNL2 protein and its predicted D-site. A) Diagram of human SMTNL2 protein showing the predicted D-site (amino acids 180-193) and the calponin homology (CH) domain (351-455). B) SMTNL2's D-site sequence aligned with known D-sites in selected JNK substrates (JUN, JUNB, ATF2, ELK1, ELK4) and in the upstream kinase MKK4. C) Conservation of the SMTNL2 JNK-docking site in other mammalian species. Residues different from the human sequence are italicized.