Table 2. Isolated CEMs of interest and their specificities.

Phages	Frequencya	Mutated Orfb	Positionb	Effects	EOP on host BIM
CEMS90	1.1%	orf33	27006–27311	Deletion of 102 aa	1.3 ± 0.1
CEMS91	8.2%	orf39	32475	Glu4Stop	6.9 ± 0.9 × 10−1
CEMS92	9.5%	orf32	26642	Glu25Stop	9.8 ± 0.5 × 10−1
CEMS93–1	17.2%	orf36	29584	Phe49: TTC→TTT	6.4 ± 0.6 × 10−1
				Rare to frequent codonc
CEMS93–2	21.8%	orf36	29593	Glu52: GAA→GAG	8.6 ± 0.5 × 10−1
				Frequent to rare codonc

^aCompared with CEMs obtained on the same BIM.

^bBased on the GenBank sequence of phage 2972.

^cAccording to the codon usage of S. thermophilus LMD-9 determined in the Codon Usage Database.