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Superimposition of the HCV-NS5BΔ21-quercetagetin complex with the HCV-NS5BΔ21-RNA complex (PDB code 4E7A) in ribbon representation (palm in red and orange, thumb in green and pale green, fingers in blue and marine). Quercetagetin and RNA are in stick representation (yellow and pink, respectively). (A) Superimposition of the global structures. (B) Zoom on the quercetagetin binding domain.
