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Rescue of the cisplatin sensitivity after USP20 depletion by USP20 or Rad17 overexpression. A, siRNA-resistant and wild-type USP20 (generated by synonymous mutations within untagged USP20 plasmid) rescued the cisplatin sensitivity after endogenous USP20 depletion, while a catalytically-defective USP20 did not. B, Rad17 overexpression rescued the cisplatin sensitivity after USP20 depletion as well. EV, empty vector.
