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. Author manuscript; available in PMC: 2014 Aug 14.
Published in final edited form as: Shock. 2013 Aug;40(2):122–128. doi: 10.1097/SHK.0b013e31829ca519

Figure 2. iNKT-cell profile within a) liver, b) blood, and c) peritoneum following CLP comparing wild type versus PD1−/− mice.

Figure 2

Figure 2

Figure 2

a) Following CLP, there was a decrease in hepatic iNKT-cells in wild type mice (* p<0.001), but an increase in hepatic iNKT-cells in PD1−/− mice (# p=0.004). b) In the peripheral circulation, although wild type mice displayed an increase in circulating iNKT-cells (* p<0.001), there was no difference in the number of circulating iNKT-cells between sham and CLP within PD1−/− mice. PD-1−/− mice had significantly fewer circulating iNKT-cells than wild type mice following CLP (# p<0.001). c) Within the peritoneal cavity, wild type mice displayed an increase in iNKT-cells following CLP (* p<0.001), whereas there was no change in the number of iNKT-cells in PD1−/− mice. Notably PD-1−/− mice had greater peritoneal iNKT-cells compared to wild type following CLP (# p<0.001).