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. 2014 Jun 18;10(8):3503–3511. doi: 10.1021/ct500162b

Table 1. Comparison of Three EGFR Crystal Structuresa.

  RMSD (Å)
  
crystal structure backbone A-loop DFG distance of ion pair (Å)
2ITW (A) 0 0 0 8.7
3W32 (T) 4.4 10.5 3.7 14.4
4I20 (I) 3.3 2.9 6.7 12.4
a

The crystal structure of 2ITW (A) is used as the reference structure for RMSD calculations.