Table 1. Comparison of Three EGFR Crystal Structuresa.
RMSD (Å) |
||||
---|---|---|---|---|
crystal structure | backbone | A-loop | DFG | distance of ion pair (Å) |
2ITW (A) | 0 | 0 | 0 | 8.7 |
3W32 (T) | 4.4 | 10.5 | 3.7 | 14.4 |
4I20 (I) | 3.3 | 2.9 | 6.7 | 12.4 |
The crystal structure of 2ITW (A) is used as the reference structure for RMSD calculations.