Table 2.
Cross reference of the 37 conserved and 4 other baculovirus genes from AcMNPV with their homologs in the nudiviruses (OrNV, GbNV, HzNV-1 and HzNV-2) and PmNV
| Function | Gene name | Nudivirus | PmNV ORF/aa | Bracoviruses and hytrosaviruses | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| ORF (aa identity/similarity%) | Accecssion no./ORF (aa identity/similarity%) | ||||||||||
| AcMNPV | OrNV | GbNV | HzNV-1 | HzNV-2 | CcBV | CiBV | MdSGHV | GpSGHV | |||
| 37 baculovirus core genes | |||||||||||
| Replication | dnapol | 65 (8/24) | 1 (12/30) | 12 (16/36) | 131 (24/46) | 18 (24/46) | 5/1091 | NA | NA | 1 (8/22) | 79 (9/24) |
| helicase | 95 (9/26) | 34 (12/31) | 88 (11/28) | 104 (16/31) | 38 (16/31) | 94/1271 | NA | NA | - | - | |
| lef-1 | 14 | - | - | - | - | - | NA | NA | - | - | |
| lef-2 | 6 | - | - | - | - | - | NA | NA | - | - | |
| alk-exo | 133 | - | - | - | - | - | NA | NA | - | - | |
| Transcription | p47 | 40 (8/20) | 20 (14/26) | 69 (10/21) | *75 (7/15) | *63 (7/15) | 14/419 | CAR31573 (17/33) | NA | - | - |
| lef-4 | 90 (8/21) | 42 (15/31) | 96 (14/33) | 98 (10/19) | 43 (10/19) | 91/470 | NA | CAR40187 (6/14) | - | - | |
| lef-5 | 99 (4/17) | 52 (9/16) | 85 (9/12) | 101 (14/23) | 40 (14/23) | 52/175 | CAT00573 (12/27) | NA | - | - | |
| lef-8 | 50 (9/24) | 64 (17/34) | 49 (18/35) | 90 (17/33) | 51 (17/33) | 23/1032 | CAR82252 (18/33) | CBB83982 (3/6) | - | - | |
| lef-9 | 62 (9/27) | 96 (15/32) | 24 (16/32) | *75 (12/21) | *63 (12/21) | 58/574 | NA | NA | - | - | |
| Oral infectivity | pif-0 (p74) | 138 (17/38) | 126 (24/43) | 45 (23/43) | 11 (26/48) | 106 (26/47) | 72/684 | CAR82260 (24/45) | CAR40192(24/45) | 39 (13/28) | 1 (12/30) |
| pif-1 | 119 (11/25) | 60 (20/34) | 52 (18/32) | 55 (22/38) | 82 (22/38) | 39/525 | NA | NA | 29 (9/20) | 102 (10/21) | |
| pif-2 | 22 (14/27) | 17 (20/35) | 66 (20/34) | 123 (25/43) | 26 (25/43) | 15/430 | NA | CAR40194 (17/32) | 89 (12/26) | 53 (20/34) | |
| pif-3 | 115 (14/23) | 107 (22/38) | 3 (24/40) | 88 (28/43) | 53 (28/43) | 93/192 | CAR82247 (20/38) | NA | 106 (14/23) | 101 (5/12) | |
| pif-4 (19 k/odv-e28) | 96 (14/31) | 33 (20/35) | 87 (17/31) | 103 (9/16) | 39 (9/16) | 96/232 | CAR31579 (17/36) | CAR40196 (21/38) | - | - | |
| pif-5 (odv-e56) | 148 (10/24) | 115 (14/32) | 5 (16/34) | 76 (22/42) | 62 (21/42) | 10/449 | CAR31578 (15/33) | CAR31577 (14/30) | - | 97 (11/25) | |
| pif-6 (ac68) | 68 (9/25) | 72 (19/42) | 55 (20/43) | 74 (20/41) | 64 (20/40) | 88/143 | CAR82241 (9/25) | NA | - | - | |
| Packaging, assembly, and release | 38 k | 98 (10/27) | 87 (14/30) | 1 (13/27) | 10 (21/38) | 108 (21/38) | 59/282 | CAR82239 (16/33) | CAR40188 (19/38) | - | - |
| p6.9 | 100 | - | - | - | - | - | NA | NA | - | - | |
| **vlf-1 | 77 (6/18) | 30 (6/15) | 80 (12/26) | 121 (10/22) | 28 (10/22) | 56/289 | CAR40203 (16/35) | CAR40190 (13/29) | - | - | |
| **vlf-1 | 77 (5/18) | 30 (4/10) | 80 (9/26) | 121 (8/22) | 28 (8/22) | 90/240 | CAR40203 (19/35) | CAR40190 (17/33) | - | - | |
| vp39 | 89 | 15 | 64 | 89 | 52 | - | NA | NA | - | - | |
| vp1054 | 54 | - | - | - | - | - | NA | NA | - | - | |
| vp91/p95 | 83 (10/23) | 106 (17/34 ) | 2 (14/29) | 46 (17/34) | 89 (17/34) | 9/675 | NA | NA | - | - | |
| gp41 | 80 | - | - | - | - | - | NA | NA | - | - | |
| p6.9 | 100 | - | - | - | - | - | NA | NA | - | - | |
| p18 | 93 | - | - | - | - | - | NA | NA | - | - | |
| p33 | 92 (9/25) | 113 (11/20) | 7 (11/23) | 13 (24/42) | 104 (25/42) | 8/228 | NA | NA | - | - | |
| p40 | 101 | - | - | - | - | - | NA | NA | - | - | |
| p48 | 103 | - | - | - | - | - | NA | NA | - | - | |
| p49 | 142 | - | - | - | - | - | NA | NA | - | - | |
| odv-ec43 | 109 | - | - | - | - | - | NA | NA | - | - | |
| odv-e18 | 143 | - | - | - | - | - | NA | NA | - | - | |
| odv-e27 | 144 | - | - | - | - | - | NA | NA | - | - | |
| desmoplakin | 66 | - | - | - | - | - | NA | NA | - | - | |
| ac53 | 53 | - | - | - | - | - | NA | NA | - | - | |
| Unknown function | ac81 | 81 (10/21) | 4 (23/41) | 14 (20/41) | 33 (32/54) | 96 (33/54) | 86/157 | NA | NA | 108 (13/26) | - |
| ac78 | 78 | - | - | - | - | - | NA | NA | - | - | |
| Other baculovirus genes | |||||||||||
| Transferase enzyme | methyltransferase | 69 (14/24) | - | - | 37 (7/14) | 93 (7/14) | 6/401 | NA | NA | - | - |
| ODV envelope | **odv-e66 | 46 (10/20) | 12 (16/32) | - | - | - | 34/551 | NA | NA | 47 (12/23) | 5 (8/14) |
| **odv-e66 | 46 (12/24) | 12 (15/30) | - | - | - | 36/635 | NA | NA | 47 (13/28) | 5 (9/16) | |
| Anti-apoptosis | iap | 27 (6/12) | 134 (7/11) | 98 (7/14) | 135 (14/23) | 15 (14/23) | 106/101 | NA | NA | 78 (13/24) | - |
| Occlusion body | polyhedrin | 8 (5/15) | 16 (11/25) | 65 (12/27) | 68 (7/20) | 70 (7/20) | #20/423 | NA | NA | 76(10/23) | - |
| polyhedrin | 8 | - | - | - | - | ##1/452 | - | - | - | - | |
*In HzNV-1 both fused in the same ORF and appear to be fused into a single gene.
**The PmNV genome contains two ORFs that are homologous to vlf-1 and to odv-e66.
#Despite the [low] identity and similarity between PmNV020 and other polyhedrons from AcMNPV and the nudiviruses, this ORF does not in fact seem to express a functional polyhedrin.
##PmNV001 is a functional homolog of polyhedrin that shows no sequence homology to AcMNPV polyhedrin.
Bracoviruses and hytrosaviruses are included for comparison.