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. 2014 Aug 1;14:560. doi: 10.1186/1471-2407-14-560

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© Tringali et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Altered expression of GM1 and GM2 synthases in melanoma cells. Correlation with patients’ survival. (A) GM1 and GM2 synthases expression assessed by Real Time PCR in melanoma cells separated in three clusters. Grey color denotes the expression of the enzyme, white color the absence. Values are the mean ± S.D. of four independent experiments. (B) Kaplan-Meier survival analysis of patients according to GM1 synthase expression, (C) according to GM2 synthase expression, and (D) according to both GM1 and GM2 synthases expression. Survival was evaluated as time from first diagnosis.