Table 3.
Predictors in a cohort-wide logistic regression analysis for a diagnosis of EoE versus non-EoE before diagnostic endoscopy
| Predictor | Univariate analysis | Multivariate analysis (N =345) | ||
|---|---|---|---|---|
| Odds ratio (95 % CI) | P value | Odds ratio (95 % CI) | P value | |
| Male sex | 2.65 (1.77–3.99) | < 0.001 | 2.47 (1.42–4.28) | 0.001 |
| Age (per year increase) | 1.00 (0.97–1.04) | 0.89 | 1.00 (0.94–1.06) | 0.93 |
| Preterm delivery (< 36 weeks) | 1.08 (0.69–1.67) | 0.73 | 1.23 (0.67–2.34) | 0.51 |
| Hospitalization in the first year of life | 0.70 (0.45–1.10) | 0.13 | 0.59 (0.31–1.11) | 0.10 |
| Reported asthma | 2.35 (1.50–3.69) | < 0.001 | 1.45 (0.80–2.63) | 0.22 |
| Reported eczema | 2.22 (1.44–3.42) | < 0.001 | 1.60 (0.91–2.79) | 0.10 |
| Reported seasonal allergy | 4.08 (2.50–6.68) | < 0.001 | 2.90 (1.63–5.18) | < 0.001 |
| Any food allergy | 5.56 (3.21–9.62) | < 0.001 | 4.58 (2.19–9.57) | < 0.001 |
| > 1 annual ear infection requiring antibiotics | 1.41 (0.95–2.09) | 0.09 | 1.04 (0.61–1.80) | 0.87 |
| Reported antibiotic allergy | 1.54 (0.96–2.48) | 0.08 | 1.77 (0.91–3.48) | 0.09 |
| Non-antibiotic drugs in the first year of life | 0.70 (0.46–1.04) | 0.08 | 0.48 (0.27–0.87) | 0.02 |
| Reported antibiotics in the first year of life | 4.48 (1.98–10.1) | < 0.001 | 4.10 (1.36–12.35) | 0.01 |
CI, confidence interval; EoE, eosinophilic esophagitis.
Bold values represent statistically significant results.