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. 2014 Apr 3;136(16):5860–5863. doi: 10.1021/ja5014344

Figure 2.

Figure 2

G4-specific alkylation. PDS-Chl (0–5 μM) was incubated with 0.2 μM oligonucleotides, for 1 h at 37 °C. Alkylated DNA (ALKY) was separated from unreacted oligonucleotides on a 15% denaturing PAGE. Oligonucleotides were detected by recording the 6-FAM fluorescence signal (λex= 488 nm).