Table 1. Mathematical model of cell identity landscape.
Landscape Term: Index Notation | Landscape Term: Matrix Notation (dim.) | Biological Interpretation |
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Total landscape. | |
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Produces cell basins of attraction. |
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External control of individual genes, i.e. inducible expression. |
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External control of specific cell basins, i.e. culturing conditions. |
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Cell switching by signals, i.e. in vivo development. |
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Number of TFs, labeled by ![]() ![]() |
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Number of cell fates, labeled by ![]() ![]() ![]() |
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State (![]() ![]() |
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State (![]() ![]() ![]() |
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Correlation between cell fate ![]() ![]() |
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Interaction strength between ![]() ![]() |
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External control of ![]() |
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External control of ![]() |
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Overlap of ![]() ![]() |
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Projection of ![]() ![]() |
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Predictivity of ![]() ![]() |
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Signal dependent coupling that drives cell fate ![]() ![]() |
This table provides a summary of the landscape model and the biological interpretation of each term. The first column is written in index notation, while the second column is the same term in matrix notation with the dimension of the term given in parenthesis. If no dimension is listed, the term is a single number.