Table 2. Partially reprogrammed cells as spurious attractors.
Cell line | Start | Goal | Highest projecting states (projection) |
A2 [17] | MEF | ESC | ESC (0.178), MSC (0.158), myoblast (0.142), MEP (0.129), blood vessel (0.113), keratinocyte (0.112), medullary thymic epithelial (−0.111), adipose - brown (−0.117), NK (−0.130), CMP (−0.138) |
B3 [17] | MEF | ESC | ESC (0.222), MSC (0.161), blood vessel (0.139), myoblast (0.138), GMP (0.127), kidney (0.111), MEP (0.107), cornea (0.107), NK (−0.129) |
BIV1+ [18] | B Cell | ESC | myoblast (0.181), prostate (0.164), MSC (0.154), MEP (0.138), keratinocyte (0.136), cornea (0.125), ESC (0.111), intestine - Paneth cell (−0.111), CMP (−0.122) |
BIV1- [18] | B Cell | ESC | ESC (0.382), EpiSC (0.184), MEP (0.160), myoblast (0.145), NSC (−0.108), T Cell (−0.115), skeletal muscle (−0.117), CMP (−0.154) |
MCV6 [18] | MEF | ESC | MEP (0.155), myoblast (0.150), ESC (0.149), keratinocyte (0.145), CLP (0.107), GMP (0.107), cornea (0.107), CMP (−0.130) |
MCV8 [18] | MEF | ESC | ESC (0.203), MEP (0.191), myoblast (0.160), cornea (0.119), prostate (0.113), skeletal muscle (−0.141), CMP (−0.142) |
Partially reprogrammed cell lines (first column) and their significant projections (2 std above noise or ) onto “natural” cell fates based on microarray data. Bold indicates 3 std above noise or . Abbreviations: CLP, Common Lymphoid Progenitor; CMP, Common Myeloid Progenitor; EpiSC, epiblast stem cell; ESC, embryonic stem cell; GMP, Granulocyte-Monocyte Progenitor; MEF, mouse embryonic fibroblast; MEP, Megakaryocyte-Erythroid Progenitor; MSC, Mesenchymal stem cells; NK, Natural Killer cells; NSC, neural stem cells.