The reaction was identical to that described in Fig. 1 except that L-Arg was not added.
A) UV-VIS spectra of starting ferrous Fe(II) (solid line), oxy-ferrous intermediate Fe(II)O2 (dashed line) and final ferric Fe(III) (dotted line) species resolved by global analysis.
Inset: Original rapid-scan diode-array data.
B) Kinetics of Fe(II) (solid line), Fe(II)O2 (dashed line) and Fe(III) (dotted line) obtained from the global analysis. Data are expressed as percentage of the total heme concentration.