Table 1.

The five behavior categories (running wheel activity, locomotion, food access, food intake and water intake) observed in naïve mice for every 24 h of days 1 and 2 and 23.5 h of day 3. One drop of water intake corresponds to 0.05 ml of water. Values are shown as means ± SEM (n = 9 and 10 for mice without and with a running wheel, respectively).

Day	Running wheel (revolutions)	Locomotion (activity counts)	Food access (access counts)	Food intake (grams)	Water intake (drops)
1	7890 ± 1327	55562 ± 4150	3176 ± 389	3.0 ± 0.4	95 ± 15
2	9408 ± 1372**	48953 ± 4714	2709 ± 274**	4.6 ± 0.4***	123 ± 18*
3	13572 ± 2342**	63083 ± 7748	2598 ± 307*	5.1 ± 0.2***	148 ± 21***
Total	30870 ± 4775	167598 ± 15138†††	8483 ± 889††	12.8 ± 0.8	365 ± 50
1	No wheel	31580 ± 2493	4699 ± 356	3.7 ± 0.4	102 ± 14
2	No wheel	26313 ± 1245*	3940 ± 237**	4.4 ± 0.4	111 ± 16
3	No wheel	24898 ± 1548*	4455 ± 320	4.5 ± 0.3***	113 ± 17
Total	-	82790 ± 4246	13094 ± 746	12.6 ± 0.9	326 ± 45

^*P < 0.05,

^**P < 0.01,

^***P < 0.001, compared with day 1 (post-hoc Bonferroni-Dunn test).

^††P < 0.01,

^†††P < 0.001, compared with no running wheel (t test).