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. 2014 Aug 14;10(8):e1003783. doi: 10.1371/journal.pcbi.1003783

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© 2014 Cao et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Inline graphic — As a function of concentration (), the two models give the same ISI (A), peak (C) and spike duration (E). These results agree qualitatively with experimental data, as shown in panels B, D and F respectively. Quantitative comparisons are generally not possible as the relationship between concentration and agonist concentration is not known. Error bars represent . Data for each MCh concentration are obtained from at least three different cells from at least two different lung slices.

As a function of concentration (), the two models give the same ISI (A), peak (C) and spike duration (E). These results agree qualitatively with experimental data, as shown in panels B, D and F respectively. Quantitative comparisons are generally not possible as the relationship between concentration and agonist concentration is not known. Error bars represent . Data for each MCh concentration are obtained from at least three different cells from at least two different lung slices.