Figure 6. Comparison of parameter-dependent frequency changes in the stochastic and deterministic models.

All curves are computed at except in panel A, which uses a variety of . Other parameters are set at their default values given in Table 1. A: as increases, oscillations in both models increase in frequency. B: as influx increases (modeled by an increase in receptor-operated calcium channel flux coefficient ), so does the oscillation frequency in both models. C: as efflux increases (modeled by an increase in plasma pump expression ), oscillation frequency decreases. D: as SERCA pump expression, , increases, so does oscillation frequency. E: as total buffer concentration, , increases, oscillation frequency decreases.