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. 2014 May 12;5(3):211–218. doi: 10.4161/nucl.29086

Table 2. Comparison of genome-wide torsion studies (“supercoilinomics”).

  Bermudez et al. Naughton et al. Kouzine et al. Teves and Henikoff
Organism Yeast Human Human Drosophilia
Substrate TMP bTMP TMP TMP
Enrichment Method Heat denuration and Exo I digestion Streptavidin pulldown Heat-glyoxal denaturation and gel electrophoresis Heat denuration and Exo I digestion
Platform Microarray Microarray Microarray PE sequencing
Assay Resolution 2 kb Unknown 250 bp Nucleotide
Effective Resolution 2 kb ~10kb ~1–5 kb 150 bp