Table 2. Histological Features and NAFLD Activity Score.
Factor | Overall(N = 242) | Fibrosis stage 0–2(N = 206) | Fibrosis stage 3–4(N = 36) | p-value |
Steatosis | <0.001 | |||
. <5% | 2(0.83) | 0(0.0) | 2(5.6) | |
. 5–33% | 85(35.1) | 85(41.3) | 0(0.0) | |
. 34–65% | 80(33.1) | 69(33.5) | 11(30.6) | |
. > = 66% | 75(31.0) | 52(25.2) | 23(63.9) | |
Lobular inflammation | <0.001 | |||
. None | 20(8.3) | 20(9.7) | 0(0.0) | |
. <2 under 20x | 166(68.6) | 159(77.2) | 7(19.4) | |
. 2–4 under 20x | 54(22.3) | 25(12.1) | 29(80.6) | |
. >4 under 20x | 2(0.83) | 2(0.97) | 0(0.0) | |
Portal inflammation | 0.030 | |||
. None | 90(37.2) | 81(39.3) | 9(25.0) | |
. Mild | 134(55.4) | 113(54.9) | 21(58.3) | |
. More than mild | 18(7.4) | 12(5.8) | 6(16.7) | |
Ballooning | <0.001 | |||
. None | 121(50.4) | 118(57.8) | 3(8.3) | |
. Few | 46(19.2) | 39(19.1) | 7(19.4) | |
. Many | 73(30.4) | 47(23.0) | 26(72.2) | |
NAS | 3.9±1.8 | 3.5±1.5 | 6.0±1.5 | <0.001 |
Values presented as Mean ± SD, or N (column %).
P-values in bold are statistically significant.