Table 1. Characters for non-diabetic participants in 14 trials that reported incident diabetes.
| Non-DMpatients | Follow-up year | Diagnosis ofincident diabetes | Intervention | NewDMcase | Numbeassignedstatin | Numberin controlgroup | New DMassignedstatin | New DMin controlgroup | |
| JUPITER | 17802/17802 | 1.9‡ | Physician reported(medication, positive OGTT,raised random glucosewith symptoms, two fastingglucose values ≥7.0 mmol/L) | Rosuvastatin 20 mgvs placebo | 486 | 8901 | 8901 | 270 | 216 |
| SPARCL | 3803/4731 | 4·9 | Two fasting glucose values≥7.0 mmol/L and at leastpost-baseline glucose≥2 mmol/l above baseline | Atorvastatin 80 mgvs placebo | 281 | 1905 | 1898 | 166 | 115 |
| HPS | 14573/20536 | 5.0 | Physician reported; medication | Simvastatin 40 mgvs placebo | 628 | 7291 | 7282 | 335 | 293 |
| ASCOT-LLA | 7773/10305 | 3.3† ‡ | WHO 1999 criteria | Atorvastatin 10 mgvs placebo | 288 | 3910 | 3863 | 154 | 134 |
| CORONA | 3534/5011 | 2.7† ‡ | Physician reported | Rosuvastatin 20 mgvs placebo | 188 | 1771 | 1763 | 100 | 88 |
| PROSPER | 5181/5804 | 3.2 | One fasting glucose value>7.0 mmol/L; medication | Pravastatin 40 mgvs placebo | 292 | 2588 | 2593 | 165 | 127 |
| GISSI-HF | 3378/4574 | 3.9‡ | Two fasting glucose values≥7.0 mmol/L | Rosuvastatin 10 mgvs placebo | 440 | 1660 | 1718 | 225 | 215 |
| 4S | 4243/4444 | 5.4‡ | Physician reported; medication;one fasting glucose value≥7.0 mmol/L | Simvastatin 20–40 mgvs placeb | 391 | 2116 | 2127 | 198 | 193 |
| WOSCOPS | 5974/6595 | 4.8 | Two fasting glucose values≥7.0 mmol/L; medication | Pravastatin 40 mgvs placebo | 168 | 2999 | 2975 | 75 | 93 |
| LIPID§ | 6997/9014 | 6.0 | One fasting glucose value≥7.0 mmol/L; medication | Pravastatin 40 mgvs placebo | 264 | 3496 | 3501 | 126 | 138 |
| AFCAPSTexCAPS | 6211/6605 | 5.2† | Physician reported;medication;one fasting glucosevalue ≥7.0 mmol/L | Lovastatin 20–40 mgvs placebo | 146 | 3094 | 3117 | 72 | 74 |
| ALLHAT-LLT | 6087/10355 | 4.8† | One fasting glucose value≥7.0 mmol/L | Pravastatin 40 mgvs no treatment | 450 | 3017 | 3070 | 238 | 212 |
| MEGA | 6086/7832 | 5.3 | Physician reported; medication;two fasting glucosevalues ≥7.0 mmol/L | Pravastatin 10–20 mgvs no treatment | 33 | 3013 | 3073 | 172 | 164 |
| GISSIPREVENZIONE | 3460/4271 | 2.0‡ | One fasting glucosevalue ≥7.0 mmol/L | Pravastatin 20 mgvs no treatment | 201 | 1743 | 1717 | 96 | 105 |
DM = diabetes mellitus; OGTT = oral glucose tolerance test; WHO = World Health Organization;
†
Data from total cohort (including diabetes at baseline).
‡
Median.
§
Includes only patients with normal fasting glycaemia at baseline.