Skip to main content
. 2014 Aug 14;9(8):e104783. doi: 10.1371/journal.pone.0104783

Table 4. Comparison of pre- and post-treatment variables in the CHC patients with SVR stratified by baseline IR.

SVR (G1 and G2) with baseline IR(n = 63) Paired t-testP values SVR (G1 and G2) without baseline IR(n = 132) Paired t-testP values
Pre- treatmentvalue Post-treatmentvalue Pre- treatmentvalue Post-treatmentvalue
Male (%) 37 (62.7%) 68 (60.1%)
Age (yr) 54.5+/−12.6 52.3+/−12.5
BMI 25.7+/−3.6 25.5+/−3.5 0.111 23.5+/−3.0 23.3+/−2.9 0.201
IL-28B rs12979860CC/CT+TT, n(CC%) 59/4(93.6%) 121/7(91.66%)
TG(mg/dL) 106.1+/−45.0 130.6+/−85.1 0.004* 96.0+/−44.7 113.1+/−65.5 0.003*
TC(mg/dL) 166. 0+/−29.7 182.4+/−40.9 <0.001* 168.3+/−32.8 184.1+/−36.1 <0.001*
HDL(mg/dL) 43.8+/−13.2 47.0+/−11.6 0.019* 51.2+/−13.6 52.4+/−14.7 0.188
LDL(mg/dL) 100.5+/−25.5 112.3+/−35.9 0.002* 100.3+/−28.6 112.9+/−31.4 <0.001*
TG/HDL 2.7+/−1.8 3.2+/−3.0 0.135 2.0+/−1.2 2.4+/−2.2 0.022*
Apo AI(g/L) 1.28+/−0.26 1.37+/−0.23 0.012* 1.45+/−0.26 1.48+/−0.26 0.111
Apo B (g/L) 0.84+/−0.17 0.87+/−0.20 0.274 0.80+/−0.19 0.88+/−0.23 <0.001*
Sugar (mg/dL) 116.3+/−44.6 120.1+/−76.5 0.601 90.2+/−8.9 95.0+/−15.7 0.001*
Insulin (µIU/mL) 19.7+/−21.9 16.8+/−27.0 0.223 6.9+/−2.8 8.0+/−4.6 0.016*
C-peptide (ng/mL) 3.9+/−2.5 3.0+/−1.5 0.019* 1.9+/−1.0 2.2+/−1.8 0.095
Hb-A1c (%; mmol/mol) 6.2+/−1.3;44+/−14 5.9+/−0.8;41+/−9 0.047* 5.6+/−0.4;37.5+/−4.5 5.6+/−0.5;37.5+/−5.5 0.546
HOMA-IR 6.2+/−11.7 4.6+/−6.7 0.04* 1.5+/−0.5 1.9+/−1.2 0.002*

*p<0.05.