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. 2014 Aug 14;9(8):e104883. doi: 10.1371/journal.pone.0104883

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© 2014 Luchting et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Ratios of Th17/CD4⁺CD25^high and Th17/CD4⁺CD25^highCD127^lowFoxP3⁺ were significantly decreased in CLBP patients as compared to healthy controls (Th17/CD4⁺CD25^high: 0.12±0.08 in CLBP patients vs. 0.33±0.23% in healthy controls, p<0.001; Fig. 7A), (Th17/CD4⁺CD25^highCD127^lowFoxP3⁺: 0.23±0.17 in CLBP patients vs. 0.64±0.79 in healthy controls, p<0.001; Fig. 7B). Ratio of TH1/TH2 cells in peripheral blood of patients with CLBP and healthy controls were tendencially decreased in patients with CLBP, but did not reach significance (9.76±7.27 in CLBP patients vs. 14.72±12.81 in healthy controls, p = 0.19, Fig. 7C).