Table 4. Odds ratios for each single-nucleotide polymorphism genotype associated with EH in the Northern Han Chinese population.
| SNP | Model | Contrast | OR (95% CI) | B | P-value |
|---|---|---|---|---|---|
| Lys109Arg | Allele comparison | G vs A | 1.079 (0.867–1.342) | 0.076 | 0.497 |
| Dominant genetic model | (GG+AG) vs AA | 1.643 (0.823–3.279) | 0.497 | 0.159 | |
| Recessive genetic model | GG vs (AG+AA) | 1.037 (0.805–1.337) | 0.036 | 0.778 | |
| Homozygote comparison | GG vs AA | 1.667 (0.826–3.364) | 0.511 | 0.154 | |
| Additive genetic model | GG vs AG vs AA | 1.081 (0.866–1.350) | 0.078 | 0.490 | |
| Gln223Arg | Allele comparison | G vs A | 1.165 (0.912–1.488) | 0.153 | 0.221 |
| Dominant genetic model | (GG+AG) vs AA | 3.697 (1.442–9.482) | 1.308 | 0.007 | |
| Recessive genetic model | GG vs (AG+AA) | 1.076 (0.818–1.415) | 0.073 | 0.599 | |
| Homozygote comparison | GG vs AA | 3.890 (1.501–10.077) | 1.358 | 0.005 | |
| Additive genetic model | GG vs AG vs AA | 1.168 (0.913–1.495) | 0.155 | 0.218 | |
| Lys656Asn | Allele comparison | C vs G | 1.460 (1.011–2.108) | 0.378 | 0.044 |
| Dominant genetic model | (CC+GC) vs GG | 1.515 (1.032–2.225) | 0.415 | 0.034 | |
| Recessive genetic model | CC vs (GC+ GG) | 0.920 (0.080–10.565) | −0.084 | 0.946 | |
| Homozygote comparison | CC vs GG | 0.966 (0.084–11.128) | −0.034 | 0.978 | |
| Additive genetic model | CC vs GC vs GG | 1.479 (1.017–2.152) | 0.392 | 0.041 |
Abbreviations: B, coefficients; CI, confidence interval; OR, odds ratio; SNP, single-nucleotide polymorphism.
ORs adjusted for age, gender, body mass index, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglyceride level, glucose level, smoking habits and drinking habits. P-values <0.05 are provided in bold to emphasize their significance.